Annual and transition report of foreign private issuers pursuant to Section 13 or 15(d)

CONSOLIDATED STATEMENTS OF LOSS AND COMPREHENSIVE LOSS

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CONSOLIDATED STATEMENTS OF LOSS AND COMPREHENSIVE LOSS - CAD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Expenses      
Research and development $ 9,392,623 $ 9,770,007 $ 8,601,864
Operating 6,212,831 5,524,500 5,315,837
Loss before the following (15,605,454) (15,294,507) (13,917,701)
Interest 130,101 163,902 197,859
Loss before income taxes (15,475,353) (15,130,605) (13,719,842)
Income tax expense (141,498) (9,374) (3,153)
Net loss (15,616,851) (15,139,979) (13,722,995)
Other comprehensive (loss) income items that may be reclassified to net loss      
Translation adjustment (180,330) (206,918) 480,935
Net comprehensive loss $ (15,797,181) $ (15,346,897) $ (13,242,060)
Basic and diluted loss per common share (cad per share) $ (0.12) $ (0.13) $ (0.12)
Weighted average number of shares (basic) 132,395,752 119,880,200 112,613,845
Weighted average number of shares (diluted) 132,395,752 119,880,200 112,613,845